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CALADO FLUVIAL

Glossary entry

Spanish term or phrase:

dep. creatinina

English translation:

creatinine clearance

Added to glossary by Janet Ross Snyder
Oct 22, 2008 22:58
15 yrs ago
15 viewers *
Spanish term

dep. creatinina

Spanish to English Medical Medical: Health Care Blood tests
Analítica: (30/09/08) RBC 4,97, WBC 10.0, HGB 13,3, HCT 40,1, VSG 10, PLATELET 307, DEP. CREATININA 73,5 ml/min, GLUCOSA 117, BUN 16.9, CREATININE 1.3 mg%, ALT 18, AST 139, NA 142, CL 111, K 4.10, LDL 89, Alb 3,8
Proposed translations (English)
5 +4 creatinine clearance
5 -1 DEP creatinine
References
Depuración de creatinina
Creatinine Clearance

Discussion

slothm Oct 23, 2008:
No doubt now. A little bit of context may have helped.
However, we now know that there is a DEP creatinine evaluation test.
This test is mandatory for exposed persons like pesticide sprayers, formulation developers, etc.
Roxanna Delgado Oct 23, 2008:
Thanks for the clarification. I guess the correct answer it's pretty clear now. Just the usual pre-op lab tests.
Janet Ross Snyder (asker) Oct 23, 2008:
pesticide exposure unknown The purpose of the physical examination was to determine if an endovascular aneurism repair (EVAR) should be done and if the patient was fit to undergo surgery. The patient had had hip surgery and a bypass, but no history of alcohol abuse or poisoning of any other kind was mentioned in the history.
Roxanna Delgado Oct 23, 2008:
Hi jlrsnyder. We really need you to clarify the mistery for us. Was this patient exposed to pesticides or not?
Rita Tepper Oct 23, 2008:
Habría que preguntarle a la asker si está traduciendo un artículo sobre pesticidas
slothm Oct 23, 2008:
There are two interpretations,
1.- Renal Clearance.
2.- The sample was obtained from a person exposed to OP pesticides. DEP is the more common metabolite of OP poisoning and meassures the rate of detoxification. It is expresed as creatinine

Proposed translations

+4
7 mins
Selected

creatinine clearance

http://www.labtestsonline.org/understanding/analytes/creatin...

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Note added at 1 hora (2008-10-23 00:56:35 GMT)
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La función renal se explora a través de la creatininemia y el clearance o depuración de la creatinina, son dos determinaciones distintas.

--------------------------------------------------
Note added at 3 horas (2008-10-23 02:23:11 GMT)
--------------------------------------------------

Alteraciones bioquímicas en sangre y orina de pacientes con litiasis renal
Características del Laboratorio en Orina de 24 Hs. de Pacientes con Litiasis Renal
Variable VN N°. Casos Media Desv. STD
Calcio H: 300 mgl24h
M:250mg/24h 11 313,273 255,866
Fósforo 340-l000mg/24h 11 566,182 261,587
Ác. Úrico 250-750 mg/24h 11 400 168,566
Oxalato H:7-44mg/24h
M: 4-31 mg/Mb 11 28,273 16,450
Vol. Urinario 5O0-2000ML/24h 11 1.113,636 530,401
Dep. Creatinina H: 98-156 ml/min
M:95-160 ml/min 11 101,727 32,398
Na 28-294mmoI/día
(0,4-4,2mmol/kg/día) 11 113,445 47,202
K 49-105mmol/día
(0,7-1,5mmol/hg/día) 11 25,236 13,240
http://www.indexmedico.com/publicaciones/journals/revistas/v...

Creatinina (mg/dL). 1,0 ± 0,9. 0,6. 4,7. Proteinuria (g/24h). 0,2 ± 0,4. 0,02. 1 ,6. Dep. creatinina. (ml/min). 92,3 ± 37,0. 32. 191. Perfil hormonal ...
www.socgastro.org.pe/biblioteca/revista/vol_27n1/a06.pdf - Páginas similares
de LFC de Rivero - 2007 - Artículos relacionados - Las 3 versiones

Funcionalismo renal (29/6/07): Volumen or/24h: 3295 ml/24h, Proteinuria cualitativa: 3+, Proteinuria en 24h: 2,67g/24h, Dep. creatinina corregida: 59,41 ml/ ...
piel-l.org/blog/archives/620 - 67k - En caché - Páginas similares
Peer comment(s):
agree Luis Elizondo Herrera
0 min
Gracias Luis!
agree Carlos Sorzano
6 mins
Gracias Carlos!
disagree slothm : Please note Rita that the list of results has two creatinine determinations, The first one is "creatinine" and the second is "DEP creatinine". Your suggestion applies to the first one.
34 mins
slothm, DEP goes for "depuración" de creatinina, the spanish translation for "clearance", though it is frequent to use the English term "clearance de creatinina"
agree David Shield : Yes, creatinine clearance makes sense, especially since the units reflect a RATE, not a simple quantity. From "depuración de creatinina".
1 hr
Gracias David!
agree Roxanna Delgado
2 hrs
Gracias Roxanna!
agree David Brown : completely!
8 hrs
Thanks David!
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "My thanks to all for the lively discussion. "
-1
32 mins

DEP creatinine

DEP is diethylphosphate, a metabolite of organophosphorous intoxication (pesticides) to be found in the urine as a metabolite after passage through the liver.
The real creatinine level in blood must be corrected due to the presence of DEP (upper case).

--------------------------------------------------
Note added at 3 hrs (2008-10-23 02:00:37 GMT)
--------------------------------------------------

http://www.ncbi.nlm.nih.gov/pubmed/11138659
Pesticide exposure and creatinine variation among young children. ... DEP was detected in 5% of the subjects
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0...
DEP was detected in 8 (18.6%) of the samples above the reference mean of 6.45 mg /g creatinine
http://www.epidem.com/pt/re/epidemiology/abstract.00001648-2...
ORGANOPHOSPHATE PESTICIDE EXPOSURES. ... All metabolite levels are reported here as microgram per gram of creatinine
http://www.occup-med.com/content/1/1/27
This may solved by creatinine correction in urine samples. .... Geometric mean for DMP and DEP levels found in the pesticide applicators of the Majes Valley
http://repositories.cdlib.org/cgi/viewcontent.cgi?article=49...
Creatinine-adjusted OP metabolite levels
http://www.rrh.org.au/articles/printviewnew.asp?ArticleID=18...
Creatinine -adjusted geometric mean dimethyl DAP concentrations were
Peer comment(s):
agree Vivian B E
35 mins
disagree Rita Tepper : please, read my comment
1 hr
Believe me, I did.
disagree Roxanna Delgado : The clue here is the result: 73.5 ml/min. That's how creatinine clearance results are given. Please read my references.
1 hr
I also read your references. Cross-checking is a standard procedure.
Something went wrong...

Reference comments

2 hrs
Reference:

Depuración de creatinina

Como muy bien acota Rita, la creatinina en sangre y la depuración de creatinina son dos cosas distintas y por eso aparecen ambas en este caso.

La capacidad de eliminación de la creatinina es un examen que compara el nivel de creatinina en la orina con el nivel de creatinina en la sangre, generalmente sobre la base de valoraciones hechas a una muestra de orina de 24 horas y a una muestra de sangre que se toma al final del período de 24 horas. La depuración o capacidad de eliminación a menudo se mide como mililitros/minuto (ml/min).

Análisis de depuración de creatinina
La depuración de creatinina se realiza para saber qué tan bien están trabajando tus riñones.

La creatinina se forma en los músculos cuando tu cuerpo produce energía. Es transportada por la sangre a los riñones, los cuales la filtran del cuerpo a la orina.

Este estudio compara los niveles de creatinina en una muestra de orina de 24 horas y con los niveles de creatinina en una muestra de sangre. De esta forma se puede saber qué tan bien están filtrando tus riñones.
Reference:

http://www.nlm.nih.gov/medlineplus/spanish/ency/article/003611.htm

http://www.paraqueestesbien.com.mx:8080/analisis/analisis_15.htm

Peer comments on this reference comment:
agree Rita Tepper : así es colega!!
17 mins
Saludos Rita.
agree slothm : Correctísimo, pero no es aplicable al caso. Ver mis referencias para intoxicaciones con pesticidas.
51 mins
Por favor, fíjate que los valores de DEP se dan en nmol/L, no en ml/min como es en este caso. Aparte dice: DEP., o sea que es una palabra abreviada. El problema estuvo en que al estar todo en mayúscula quizás eso se presta a confusión.
Something went wrong...
8 hrs
Reference:

Creatinine Clearance

Many laboratories nowadays calculaute the creatinine clearance or Glomerular Filtration Rate only using the plasma creatinine, using the Cockcroft- Gault Formula, an example of which is given here

http://www.medalreg.com/qhc/medal/ch14/14_02/14-02-07-ver9.p...
Peer comments on this reference comment:
agree Rita Tepper
4 hrs
Something went wrong...
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