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indivíduos

English translation: individuals

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Spanish term or phrase:indivíduos
English translation:individuals
Entered by: Charles Davis

06:17 Jul 16, 2019
Spanish to English translations [PRO]
Medical - Medical (general) / Cholestorol and statins
Spanish term or phrase: indivíduos
En ausencia de PCSK9, el receptor es «reciclado», siendo transportado a la membrana celular, donde puede continuar captando partículas LDL.
En sentido inverso, se han descrito mutaciones con defecto de síntesis de PCSK9, que presenta un fenotipo opuesto al de la hipercolesterolemia familiar: reducción de cifras de colesterol circulante y descenso notable de la incidencia de cardiopatía isquémica.
Se han descrito unos pocos individuos homocigotos o dobles heterocigotos de alelos nulos de PCSK9, con niveles de PCSK9 indetectables.

Not sure about "individuos" in this particular sentence. Are they talking about human individuals or individual alleles? Thoughts?

TIA, Juliette
ServingMed.com
Netherlands
Local time: 23:18
individuals
Explanation:
It means people (or in theory other organisms) who have this genetic characteristic. "Individuos" as a noun must means that.

"Homocigoto se refiere a la composición genética de una característica específica en un organismo diploide. Cada alelo de un gen en particular se hereda de cada progenitor. Si ambos alelos para ese gen en particular son iguales, entonces el organismo es homocigoto."
https://www.genome.gov/es/genetics-glossary/Homocigoto

"A heterozygote is an individual having two different alleles at a genetic locus; a homozygote is an individual having two copies of the same allele at a locus."
https://www.blackwellpublishing.com/ridley/a-z/Heterozygote_...

You could call them homozygous individuals (, or indeed homozygotic individuals, and you even find homozygote individuals.

"Individuals have two copies of genes on the autosomes (and in females on the X chromosomes), in homozygous individuals (homozygotes) both copies of the allele are identical. Homozygous individuals will always pass their allele onto any children."
https://www.genomicseducation.hee.nhs.uk/glossary/homozygous...

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Note added at 15 mins (2019-07-16 06:32:47 GMT)
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I highlighted the wrong phrase in the second reference, but the principle is the same.

--------------------------------------------------
Note added at 32 mins (2019-07-16 06:49:45 GMT)
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The word "homozygote" can't be applied to alleles, but only to organisms.
Selected response from:

Charles Davis
Spain
Local time: 23:18
Grading comment
Many thanks.
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +9individuals
Charles Davis


Discussion entries: 1





  

Answers


14 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +9
individuals


Explanation:
It means people (or in theory other organisms) who have this genetic characteristic. "Individuos" as a noun must means that.

"Homocigoto se refiere a la composición genética de una característica específica en un organismo diploide. Cada alelo de un gen en particular se hereda de cada progenitor. Si ambos alelos para ese gen en particular son iguales, entonces el organismo es homocigoto."
https://www.genome.gov/es/genetics-glossary/Homocigoto

"A heterozygote is an individual having two different alleles at a genetic locus; a homozygote is an individual having two copies of the same allele at a locus."
https://www.blackwellpublishing.com/ridley/a-z/Heterozygote_...

You could call them homozygous individuals (, or indeed homozygotic individuals, and you even find homozygote individuals.

"Individuals have two copies of genes on the autosomes (and in females on the X chromosomes), in homozygous individuals (homozygotes) both copies of the allele are identical. Homozygous individuals will always pass their allele onto any children."
https://www.genomicseducation.hee.nhs.uk/glossary/homozygous...

--------------------------------------------------
Note added at 15 mins (2019-07-16 06:32:47 GMT)
--------------------------------------------------

I highlighted the wrong phrase in the second reference, but the principle is the same.

--------------------------------------------------
Note added at 32 mins (2019-07-16 06:49:45 GMT)
--------------------------------------------------

The word "homozygote" can't be applied to alleles, but only to organisms.

Charles Davis
Spain
Local time: 23:18
Native speaker of: English
PRO pts in category: 804
Grading comment
Many thanks.

Peer comments on this answer (and responses from the answerer)
agree  YESHWANT UMRALKAR: notwithstanding the rather detailed explanation, grammatically it is pretty much obvious that the attributes "homocigotos o dobles heterocigotos" qualify the noun individuos, hence individuals
1 hr
  -> Thanks! Yes, I agree; it's essentially a grammatical point. The rest is just background.
agree  Muriel Vasconcellos
1 hr
  -> Thanks, Muriel :-)
agree  liz askew: Indeed. Pretty straightforward.
1 hr
  -> Thanks, Liz :-)
agree  José Patrício: The main difference between homozygous and heterozygous is that homozygous individuals carry two identical alleles whereas heterozygous individuals - https://pediaa.com/difference-between-homozygous-and-heteroz...
1 hr
  -> Thanks, Jose :-)
agree  María Patricia Arce
3 hrs
  -> Thanks, María Patricia :-)
agree  Elisa Lopez Schiaffino
4 hrs
  -> Thanks, Elisa :-)
agree  Maria Kisic
6 hrs
  -> Thanks, Maria :-)
agree  Clarkalo
10 hrs
  -> Many thanks, Clarkalo :-) Do you know the expression "rectificar es de sabios"?
agree  JohnMcDove
2 days 15 hrs
  -> Gracias, John ;-)
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