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  3. Biology (-tech,-chem,micro-)

a tether molecule

13:29 Dec 10, 2021
English to French translations [PRO]
Science - Biology (-tech,-chem,micro-) / Biosensor based on a tethered particle
English term or phrase: a tether molecule
contexte
" The present invention relates generally to a biosensor technique based on detecting the presence of an analyte based on changes in motion of a particle attached by a tether to (tethered to) a surface."

"The tethered particle motion (TPM) technique is based on measurements of the motion of particles tethered to a surface, where TPM experiments are reported on proteins that bind to a DNA tether, in order to reveal how the proteins change the DNA conformation. In such studies, measures are taken to avoid not-via-the-tether binding of the particle to the surface, because a particle that is bound to the surface in another way than via the tether, does not give information about the tether"

"A biosensor device for sensing an analyte using tethered particle motion, the biosensor device having a surface and a tether molecule bound at a first end to the surface and bound at a second end to a particle to form a tethered particle, wherein the particle or the surface is functionalized with an analyte-binding moiety"
ghadir madani
Tunisia
Local time: 01:32


Summary of answers provided
4 +1molécule liée
Drmanu49


  

Answers


2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
molécule liée


Explanation:
influence de la présence de défauts locaux présents sur l'ADN ...
https://hal-univ-tlse3.archives-ouvertes.fr › tel-01384604
... unique grâce à la technique haut-débit de "Tethered Particle Motion" (HT-TPM). ... séquence spécifique ou la liaison d'une protéine sur la molécule d'ADN.

abstract_ P Simonet
http://nonlineaire.univ-lille1.fr › Contributions › a...
PDF
liaisons hydrogène entre paires de bases complémentaires. ... l'approche molécule unique de TPM (« Tethered Particle Motion »), technique bien maîtrisée.

Drmanu49
France
Local time: 02:32
Works in field
Native speaker of: Native in EnglishEnglish, Native in FrenchFrench
PRO pts in category: 538
Notes to answerer
Asker: Bonjour, Dans le contexte de ma traduction, "the tether molecule" assure la liaison à la particule pour ainsi former une particule liée "tethered particle" via "the tether molecule".


Peer comments on this answer (and responses from the answerer)
agree  Lionel-N
1 day 1 hr
  -> Thanks Lio!
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