@Stuart&Aida 20:49 Mar 23, 2022
The author of this query wants to know how well the products of this company are suited for application through a feeding tube. In order to be applied through a feeding tube, an oral tablet must be crushable/grindable (which is usually done in a mortar; "Mörserbarkeit") in order to produce particles which are tiny enough to be pushed through the tube. It must be suspendable [a suspension is composed of tiniest particles which are distributed ("suspended") in a liquid medium – as opposed to a solution where the solid component is chemically dissolved down to the molecular level] ("Suspendierbarkeit"). If the tablet is poorly suspendable, the drug substance will settle at the bottom of the mixing jar, and cannot be drawn into a syringe for application. And, third, the tablet particles must be able to pass through the feeding tube (Sondengängigkeit). I am not sure if Sondengängigkeit is really more than the sum of suitability for grinding and suspending, but there may be other properties like electrostatic or mechanic adhesion which prevent the substance from passing through the tube. Does that help at all? |