imidazole(in)e α-adrenoceptor agent

Russian translation: имидазоловые и имидазолиновые лиганды α-адренорецепторов

16:55 Dec 8, 2022
English to Russian translations [PRO]
Medical: Pharmaceuticals
English term or phrase: imidazole(in)e α-adrenoceptor agent
Здравствуйте. Помогите перевести imidazole(in)e α-adrenoceptor agent в контексте: The imidazole(in)e α-adrenoceptor agents have a significance in pharmacological therapy for the conditions under which platelet hyperreactivity to adrenaline occurs.
Iana Osipova
Russian Federation
Local time: 18:51
Russian translation:имидазоловые и имидазолиновые лиганды α-адренорецепторов
Explanation:
В источнике или вопросе опечатка: вместо imidazole(in)e должно быть imidazol(in)e, т.е. как имидазолы, так и имидазолины. И речь в данном случае не об имидазолиновых рецепторах, а об имидазолах и имидазолинах, действующих на альфа-адренорецепторы. Наконец, вместо "препарат, действующий на рецептор" достаточно сказать "лиганд".
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Anton Konashenok
Czech Republic
Local time: 17:51
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Selected automatically based on peer agreement.
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Summary of answers provided
4 +2имидазоловые и имидазолиновые лиганды α-адренорецепторов
Anton Konashenok
Summary of reference entries provided
see
liz askew

  

Answers


4 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
имидазоловые и имидазолиновые лиганды α-адренорецепторов


Explanation:
В источнике или вопросе опечатка: вместо imidazole(in)e должно быть imidazol(in)e, т.е. как имидазолы, так и имидазолины. И речь в данном случае не об имидазолиновых рецепторах, а об имидазолах и имидазолинах, действующих на альфа-адренорецепторы. Наконец, вместо "препарат, действующий на рецептор" достаточно сказать "лиганд".

Anton Konashenok
Czech Republic
Local time: 17:51
Specializes in field
Native speaker of: Native in RussianRussian, Native in EnglishEnglish
PRO pts in category: 143
Grading comment
Selected automatically based on peer agreement.

Peer comments on this answer (and responses from the answerer)
agree  Igor Andreev
8 hrs
  -> Спасибо, Игорь

agree  Ilya Razmanov: я бы скорее сказал "имидазольные", а не "имидазолиновые", в остальном полностью согласен
7 days
  -> Спасибо, Илья
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Reference comments


7 mins
Reference: see

Reference information:
Effects of Imidazoline and Nonimidazoline α2-Adrenergic ...
https://scialert.net › fulltext
Imidazoline α2-adrenergic agents also exert complex effects on mammalian platelet aggregation (Hikasa et al., 1999; Yokota et al., 2013a, b). Although, the ...

Clonidine and ST-91 May Activate Imidazoline Binding Sites ...
https://www.ahajournals.org › doi › full › 01.hyp.30.1.83
by S Mukaddam-Daher · 1997 · Cited by 28 — The ****imidazoline**** receptors are a new class of receptors that are distinct from α2-adrenergic receptors because they show low affinity for the catecholamines ...

Effects of imidazoline and nonimidazoline α-adrenoceptor ...
https://avmajournals.avma.org › ajvr › ajvr.81.2.159.xml
by T Matsukawa · 2020 · Cited by 3 — The α2-adrenoceptor antagonists and certain imidazoline α-adrenergic agents including phentolamine, yohimbine, atipamezole,

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Note added at 9 mins (2022-12-08 17:04:41 GMT)
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Effects of imidazoline and nonimidazoline α-adrenoceptor ...
https://pubmed.ncbi.nlm.nih.gov › ...
by T Matsukawa · 2020 · Cited by 3 — Imidazoline α-adrenergic agents may have clinical use for conditions in which there is platelet reactivity to adrenaline. Xylazine, medetomidine, and ...

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Note added at 12 mins (2022-12-08 17:07:44 GMT)
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Периферические эффекты взаимодействия α2 ...
https://lib.ossn.ru › jour › article › download
PDF
by АВ Мальцев · 2019 · Cited by 1 — Results: It has been shown that α2-adrenergic and imidazoline receptor ... Ca2+-currents by themselves, but their effects do not develop

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Note added at 14 mins (2022-12-08 17:09:09 GMT)
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sorry, here is the site:

https://lib.ossn.ru/jour/article/view/591/406

liz askew
United Kingdom
Works in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 4
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